{Reference Type}: Case Reports
{Title}: Uterine Fibroid-Associated Massive Pulmonary Embolism: A Report of Two Cases.
{Author}: Brown D;Ghalib N;Wu J;Shahzadi A;Simpson T;Sharma A;Bejugam VR;Soodhan K;Thachil R;
{Journal}: Cureus
{Volume}: 16
{Issue}: 6
{Year}: 2024 Jun
暂无{DOI}: 10.7759/cureus.62436
{Abstract}: This report details cases of uterine fibroid-associated deep vein thrombosis leading to massive pulmonary embolism, as well as the likely associated physiology. Two women, aged 33 and 37, presented with fibroid-associated pulmonary embolism. They both had large uterine sizes and no underlying thrombophilia. Case 1 had an uncomplicated course, whereas Case 2 had a course complicated by cardiac arrest and prolonged recovery. The presence of fibroids enhances coagulation and platelet adhesion. Mechanical compression also plays a role in predisposing to thrombosis. There may be a role for preoperative screening, especially in those with an elevated estimated uterine weight.