{Reference Type}: Journal Article {Title}: Trematode Genomics and Proteomics. {Author}: Rinaldi G;Loukas A;Sotillo J; {Journal}: Adv Exp Med Biol {Volume}: 1454 {Issue}: 0 {Year}: 2024 {Factor}: 3.65 {DOI}: 10.1007/978-3-031-60121-7_13 {Abstract}: Trematode infections stand out as one of the frequently overlooked tropical diseases, despite their wide global prevalence and remarkable capacity to parasitize diverse host species and tissues. Furthermore, these parasites hold significant socio-economic, medical, veterinary and agricultural implications. Over the past decades, substantial strides have been taken to bridge the information gap concerning various "omic" tools, such as proteomics and genomics, in this field. In this edition of the book, we highlight recent progress in genomics and proteomics concerning trematodes with a particular focus on the advances made in the past 5 years. Additionally, we present insights into cutting-edge technologies employed in studying trematode biology and shed light on the available resources for exploring the molecular facets of this particular group of parasitic helminths.