{Reference Type}: Journal Article
{Title}: One-year outcomes in COVID-19 and non-COVID-19 intensive care unit survivors.
{Author}: Heesakkers H;van der Hoeven JG;Corsten S;Janssen I;Ewalds E;Simons KS;de Blauw M;Rettig TCD;Jacobs C;van Santen S;Slooter AJC;van der Woude MCE;Zegers M;van den Boogaard M;
{Journal}: J Crit Care
{Volume}: 84
{Issue}: 0
{Year}: 2024 Jul 13
{Factor}: 4.298
{DOI}: 10.1016/j.jcrc.2024.154858
{Abstract}: <B>OBJECTIVE: </B>To determine differences in one-year multi-domain health outcomes in COVID-19 and non-COVID-19 intensive care unit (ICU) survivors.<BR><B>METHODS: </B>Adult ICU survivors treated for COVID-19 were compared to a control group consisting of survivors admitted for respiratory distress due to other causes, i.e. non-COVID-19 ARDS or pneumonia. Occurrence of physical (frailty, fatigue, physical symptoms), mental (anxiety, depression, post-traumatic stress) and cognitive symptoms, and quality of life (QoL) scores were measured, using validated questionnaires, before and one year after ICU treatment.<BR><B>RESULTS: </B>In total, 506 COVID-19 survivors could be compared to 228 non-COVID-19 survivors. At one-year follow-up, COVID-19 ICU survivors had less physical (76.2% vs. 86.9%, p = 0.001) and mental symptoms (32.0% vs. 47.1%, p < 0.001) than the control group. Cognitive symptoms were comparable (22.5% vs. 17.2%, p = 0.12). However, compared to pre-ICU health symptoms and scores, COVID-19 survivors experienced an increase in symptom occurrence rates in all domains and a decrease in QoL, whereas the control group only experienced an increase in mental and cognitive symptoms, with a similar QoL at one-year follow-up.<BR><B>CONCLUSIONS: </B>COVID-19 ICU survivors experience equal or less health problems but a greater decline in QoL one year after ICU admission compared to non-COVID-19 ARDS or pneumonia survivors.