{Reference Type}: Journal Article
{Title}: Energy-transfer Enabled Divergent Synthesis of Polycyclic γ-Sultines.
{Author}: Zhou P;Zhang Y;Ma X;Yang X;Fang X;Lu X;Shu C;
{Journal}: Chemistry
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 14
{Factor}: 5.02
{DOI}: 10.1002/chem.202401369
{Abstract}: A visible-light-initiated energy-transfer enabled radical cyclization for the divergent synthesis of polycyclic γ-sultine derivatives has been developed. The reaction provides an alternative and expeditious access to benzofused γ-sultine frameworks, the analogues of γ-lactones and γ-sultones, and features good functional group compatibility, mild reaction conditions and excellent diastereoselectivity. The robustness and application potential of this method have also been successfully displayed by two gram-scale reactions and the synthesis of polycyclic sultones. Mechanistic studies indicated the transformations through a possible energy-transfer enabled intramolecular radical homolytic substitution or hydrogen atom transfer process mainly.