{Reference Type}: Journal Article
{Title}: STOP-Bang questionnaire in patients hospitalized with acute symptomatic pulmonary embolism.
{Author}: Briceño W;Barbero E;Mañas E;González S;García-Ortega A;Oscullo G;García-Sánchez A;Cano-Pumarega I;Martinez-Garcia MÁ;Jimenez D;
{Journal}: Sleep
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 12
{Factor}: 6.313
{DOI}: 10.1093/sleep/zsae158
{Abstract}: <B>OBJECTIVE: </B>The STOP-Bang questionnaire is a validated screening tool for obstructive sleep apnea (OSA). We conducted this study to validate it among patients hospitalized with acute symptomatic pulmonary embolism (PE).<BR><B>METHODS: </B>This prospective cohort study enrolled consecutive stable patients with acute PE who underwent an overnight sleep study within 7 days after diagnosis. Our outcomes were: i) the STOP-Bang questionnaire's utility for risk stratification, ii) the discrimination of the STOP-Bang questionnaire categories, iii) the false negative rate of STOP-Bang questionnaire prediction, and iv) the clinical utility of the STOP-Bang questionnaire to exclude OSA. We also calculated the test performance characteristics to predict OSA.<BR><B>RESULTS: </B>During the study period, 268 patients completed a sleep study. OSA was found in 47% of patients. OSA incidence in low-, moderate-, and high-risk STOP-Bang groups was 22.4%, 48.2%, and 61.5%, respectively (P <0.001). The area under the receiver operating characteristics curve of the STOP-Bang questionnaire for risk of OSA was 0.65. The false negative rate of a low-risk STOP-Bang questionnaire result to rule out OSA was 22.4% and the clinical utility was 21.6%. The sensitivity was 89.8% (97.2% for men and 80.4% for women).<BR><B>CONCLUSIONS: </B>The STOP-Bang questionnaire showed poor discrimination for the risk of OSA in hospitalized patients with acute symptomatic PE. It had a high false negative rate and a low clinical utility. The STOP-Bang questionnaire had a good sensitivity in men, and might be used to rule out OSA in this population.