{Reference Type}: Case Reports {Title}: Guillain-Barre Syndrome as an Atypical Early Presentation of Adult-Onset Still's Disease: A Case Report. {Author}: Al Kaakour J;El-Kojok C;El Mustapha S;Kheirallah JC; {Journal}: Cureus {Volume}: 16 {Issue}: 6 {Year}: 2024 Jun 暂无{DOI}: 10.7759/cureus.62162 {Abstract}: Adult-onset Still's disease (AOSD) is a rare auto-inflammatory disorder with unknown pathophysiology. Although having a heterogeneous clinical spectrum, the major features of AOSD include fever, rash, and arthritis or arthralgia. Neurological involvement is rare in AOSD with aseptic meningitis being the most common presentation. Guillain-Barre syndrome (GBS) has never been reported as an early presentation of AOSD. Herein, we describe the case of a patient presenting with GBS and fever of unknown origin who was soon diagnosed with AOSD and improved with corticosteroid therapy.