{Reference Type}: Journal Article
{Title}: Two new compounds isolated from the aerial parts of gastrodia elata blume.
{Author}: Du C;Wang W;Wei C;Yang W;Cheng L;Hou Y;Liu X;Zhu G;Li X;Xu J;
{Journal}: Nat Prod Res
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 11
{Factor}: 2.488
{DOI}: 10.1080/14786419.2024.2364238
{Abstract}: Two new aromatic compounds, namely gastupdin A (1), and gastupdin B (2), together with three known compounds, arundin(3), phomosines B (4) and monocillin IV (5), were isolated from the aerial parts of Gastrodia elata Blume. The structures of the new compounds were confirmed through spectral analyses including NMR, HR-ESI-MS, ECD, UV, and IR. All isolated compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death in Human Neuroblastoma Cells, with curcumin as the positive control, however, the activity of all compounds was weaker than the positive control, showing no significant activity.