{Reference Type}: Case Reports
{Title}: Aortic root dilation in acromegaly.
{Author}: Yeboah-Kordieh YA;Arif W;Weisman D;Salvatori R;
{Journal}: BMJ Case Rep
{Volume}: 17
{Issue}: 7
{Year}: 2024 Jul 10
暂无{DOI}: 10.1136/bcr-2024-260204
{Abstract}: Previous studies have linked persistent elevations in growth hormone (GH) and insulin-like growth factor-1 (IGF-1) to cardiac abnormalities including aortic root dilation. Guidelines in the management of this dilation below the size recommended for surgery have not been well defined but follow-up and intervention when appropriate could be life-saving. We report the case of a man in his 60s who had been living with undiagnosed acromegaly for many years. His initial assessment through point-of-care ultrasound raised concerns about potential cardiac enlargement, prompting further investigation with a formal echocardiogram, which revealed a significant aortic root dilation measuring 4.5 cm. Subsequent blood tests confirmed elevated levels of IGF-1. Brain MRI showed a focal lesion in the pituitary gland, which was surgically resected, confirming the diagnosis of a GH-secreting pituitary adenoma. One year after surgery, a repeat CT angiogram of the chest demonstrated a stable size of the aortic root aneurysm.