{Reference Type}: Case Reports
{Title}: Underdosed generic specialty medications: A prescription for patient harm?
{Author}: Okuda DT;Burgess KW;Moog TM;Patel MA;
{Journal}: Mult Scler Relat Disord
{Volume}: 88
{Issue}: 0
{Year}: 2024 Aug 5
{Factor}: 4.808
{DOI}: 10.1016/j.msard.2024.105760
{Abstract}: The use of generic specialty medications amongst individuals with multiple sclerosis (MS) has expanded due to an increase in the number of available agents. We describe a woman who was denied continued use of brand name teriflunomide (AubagioⓇ), despite being clinically stable for 2.5 years, and switched to generic teriflunomide. She experienced a significant spinal cord exacerbation within a few months of starting treatment. We analyzed 3 generic teriflunomide agents, including the one used for treatment, in addition to AubagioⓇ. The generic teriflunomide used by our patient contained 55.5 % content of the labeled amount, well below U.S. FDA specifications.