{Reference Type}: Journal Article
{Title}: Quercetin in Oncology: A Phytochemical with Immense Therapeutic Potential.
{Author}: Kamal R;Paul P;Thakur S;Singh SK;Awasthi A;
{Journal}: Curr Drug Targets
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 10
{Factor}: 2.937
{DOI}: 10.2174/0113894501292466240627050638
{Abstract}: Quercetin is a natural flavonoid with various pharmacological actions such as anti-inflammatory, antioxidant, antimicrobial, anticancer, antiviral, antidiabetic, cardioprotective, neuroprotective, and antiviral activities. Looking at these enormous potentials, researchers have explored how they can be used to manage numerous cancers. It's been studied for cancer management due to its anti-angiogenesis, anti-metastatic, and antiproliferative mechanisms. Despite having these proven pharmacological activities, the clinical use of quercetin is limited due to its first-- pass metabolism, poor solubility, and bioavailability. To address these shortcomings, researchers have fabricated various nanocarriers-based formulations to fight cancer. The present review overshadows the pharmacological potential, mechanisms, and application of nanoformulations against different cancers.