{Reference Type}: Journal Article
{Title}: B cells! Don't go the wrong way in this tumor.
{Author}: Pupier G;Sautès-Fridman C;
{Journal}: Immunity
{Volume}: 57
{Issue}: 7
{Year}: 2024 Jul 9
{Factor}: 43.474
{DOI}: 10.1016/j.immuni.2024.06.007
{Abstract}: The association of tertiary lymphoid structures (TLSs) with survival and immunotherapy response brought B cells to center stage. In a pan-cancer B cells atlas in Science, Ma et al. show that germinal center reaction generating anti-tumor antibody-secreting cells (ASCs) from B memory cells in mature TLSs co-exist in tumors with extra-follicular reaction generating auto-reactive ASCs from memory B cells in immature TLSs.