{Reference Type}: Journal Article {Title}: The History of Agrobacterium Rhizogenes: From Pathogen to a Multitasking Platform for Biotechnology. {Author}: Loyola-Vargas VM;Méndez-Hernández HA;Quintana-Escobar AO; {Journal}: Methods Mol Biol {Volume}: 2827 {Issue}: 0 {Year}: 2024 暂无{DOI}: 10.1007/978-1-0716-3954-2_4 {Abstract}: Agrobacterium's journey has been a roller coaster, from being a pathogen to becoming a powerful biotechnological tool. While A. tumefaciens has provided the scientific community with a versatile tool for plant transformation, Agrobacterium rhizogenes has given researchers a Swiss army knife for developing many applications. These applications range from a methodology to regenerate plants, often recalcitrant, to establish bioremediation protocols to a valuable system to produce secondary metabolites. This chapter reviews its discovery, biology, controversies over its nomenclature, and some of the multiple applications developed using A. rhizogenes as a platform.