{Reference Type}: Journal Article
{Title}: Clinical therapeutic effect of self-prescribed Sanhanchushi Tongbi on lumbar disc herniation.
{Author}: Yao C;He B;Zhou J;Xie L;
{Journal}: World J Clin Cases
{Volume}: 12
{Issue}: 18
{Year}: 2024 Jun 26
{Factor}: 1.534
{DOI}: 10.12998/wjcc.v12.i18.3444
{Abstract}: <B>BACKGROUND: </B>Lumbar disc herniation (LDH) commonly occurs during spinal surgery; LDH is on the increase in younger patients and is classified as "paralysis" and "back pain." Sanhanchushi Tongbi (SPST) is a customized prescription. It disperses cold, relieves pain, removes cold from the meridians and viscera, and treats neuropathic pain. However, few studies have investigated its mechanism of pain relief.<BR><B>OBJECTIVE: </B>To observe the clinical therapeutic effects on LDH treated with self-prescribed SPST.<BR><B>METHODS: </B>A total of 211 patients with LDH syndrome were divided into two groups: 107 patients in the control group were treated with conventional massage combined with traction, and 104 patients in the observation group were treated with a combination of the control regimen and self-prescribed oral SPST. The patients were treated for 4 wk. Indices of traditional Chinese medicine (TCM) syndrome score and serum inflammatory factor levels were measured.<BR><B>RESULTS: </B>After therapy, the TCM syndrome score in the observation group was significantly lower than that in the control group (P < 0.05). The main symptoms, clinical signs, daily activities, and Japanese Orthopedic Association scores in the observation group were significantly higher than those in the control group after therapy (P < 0.05). The levels of tumor necrosis factor-α, interleukin-6, and C-reactive protein were lower in the observation group than in the control group (P < 0.05). In the observation group, superoxide dismutase levels were significantly higher, whereas malondialdehyde levels were significantly lower, compared with the control group (P < 0.05). The overall efficacy rate in the observation group was 96.15%, which was substantially higher than that in the control group (88.79%; P < 0.05).<BR><B>CONCLUSIONS: </B>Self-prescribed SPST can reduce the levels of inflammatory and pain-causing factors as well as lumbar pain in patients with LDH.