{Reference Type}: Journal Article
{Title}: Aframomumlabdane, a new bislabdane diterpenoid from Aframomum arundinaceum (zingiberaceae).
{Author}: Ango PY;Ghoda AW;Abega DF;Mapitse R;Kuete V;Ngadjui BT;Fotso GW;Kapche DWFG;
{Journal}: Nat Prod Res
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 8
{Factor}: 2.488
{DOI}: 10.1080/14786419.2024.2372847
{Abstract}: A previously undescribed bislabdane diterpenoid namely aframomumlabdane (1), was isolated from the seed of Aframomum arundinaceum together with seven known compounds (2 - 8). Their structures were established based on a comprehensive analysis of HR-ESI-MS, in conjunction with their 1D and 2D-NMR data. Compound 1 was evaluated for its cytotoxic activity against four cancer cell lines: A549, HepG2, SPC212 and DLD-1. The best activity was observed against SPC212 lung cancer cell line with an IC50 value of 0.52 μM.