{Reference Type}: Journal Article {Title}: Innovations in the Treatment of Spinal Cerebrospinal Fluid Leaks. {Author}: Zappi K;Giantini-Larsen A;Yan J;Konate M;Garton ALA;Knopman J;Stieg PE;Salama G;Park JK; {Journal}: World Neurosurg {Volume}: 187 {Issue}: 0 {Year}: 2024 Jul {Factor}: 2.21 {DOI}: 10.1016/j.wneu.2024.03.112 {Abstract}: Spontaneous spinal cerebrospinal fluid (CSF) leaks are uncommon but can be neurologically debilitating. When initial treatments fail, definitive repair or closure of the leak is indicated. Depending upon the type of leak present, innovative strategies for their treatment have been developed. Among them are open surgical techniques using a transdural approach for the closure of ventral CSF leaks, minimally invasive tubular techniques for the reduction and repair of lateral meningeal diverticula, and endovascular embolization of CSF-venous fistulas. Illustrative cases demonstrating the indications for and implementation of these techniques are provided.