{Reference Type}: Journal Article {Title}: Microalgae-mediated bioremediation: current trends and opportunities-a review. {Author}: Ali SS;Hassan LHS;El-Sheekh M; {Journal}: Arch Microbiol {Volume}: 206 {Issue}: 8 {Year}: 2024 Jul 5 {Factor}: 2.667 {DOI}: 10.1007/s00203-024-04052-x {Abstract}: Environmental pollution poses a critical global challenge, and traditional wastewater treatment methods often prove inadequate in addressing the complexity and scale of this issue. On the other hand, microalgae exhibit diverse metabolic capabilities that enable them to remediate a wide range of pollutants, including heavy metals, organic contaminants, and excess nutrients. By leveraging the unique metabolic pathways of microalgae, innovative strategies can be developed to effectively remediate polluted environments. Therefore, this review paper highlights the potential of microalgae-mediated bioremediation as a sustainable and cost-effective alternative to conventional methods. It also highlights the advantages of utilizing microalgae and algae-bacteria co-cultures for large-scale bioremediation applications, demonstrating impressive biomass production rates and enhanced pollutant removal efficiency. The promising potential of microalgae-mediated bioremediation is emphasized, presenting a viable and innovative alternative to traditional treatment methods in addressing the global challenge of environmental pollution. This review identifies the opportunities and challenges for microalgae-based technology and proposed suggestions for future studies to tackle challenges. The findings of this review advance our understanding of the potential of microalgae-based technology wastewater treatment.