{Reference Type}: Case Reports {Title}: Rothia dentocariosa endocarditis with brain abscess and splenic abscess: case report and brief review. {Author}: Zheng X;Liu F;Ma Q;Li J;Ma H; {Journal}: Front Cardiovasc Med {Volume}: 11 {Issue}: 0 {Year}: 2024 {Factor}: 5.846 {DOI}: 10.3389/fcvm.2024.1370736 {Abstract}: Rothia dentocariosa is a conditionally pathogenic bacterium that may cause infective endocarditis (IE) in selected patients and give rise to a variety of clinical complications, albeit it is not a common IE pathogen. We present the case of a patient diagnosed with Rothia dentocariosa-associated IE secondary to influenza B and thrombocytopenic purpura. The blood culture revealed Rochebacterium caries, cardiac ultrasound detected vegetation, while brain and spleen abscesses manifested and progressively deteriorated. Despite a suboptimal response to anti-infective therapy, the patient ultimately underwent aortic valve replacement. Discharge from the hospital was achieved upon control of the brain abscess and spleen abscess.