{Reference Type}: Case Reports {Title}: Mammary Paget's Disease as a Sign of Local Recurrence Two Decades Following Breast Conservation and Adjuvant Therapy for Early Stage Breast Cancer. {Author}: Afzal RJ;Basree MM;Howard SP;Xu J;Wilke LG;Anderson BM; {Journal}: Cureus {Volume}: 16 {Issue}: 6 {Year}: 2024 Jun 暂无{DOI}: 10.7759/cureus.61521 {Abstract}: Reports of mammary Paget's disease (MPD) as a manifestation of breast cancer recurrence are rare. MPD presents a particular challenge when emerging more than two decades after a breast cancer treated with evidence-based therapy. There is a broad spectrum of non-malignant causes for dermatitis of the nipple during the initial presentation that may delay cancer work-up. This case highlights the MPD work-up and management in the context of a personal history of breast cancer. This unique clinical presentation emphasizes the importance of vigilant cancer surveillance for timely intervention, especially for a presumed cured cancer.