{Reference Type}: Journal Article
{Title}: [A case of pleural metastasis of malignant peripheral nerve sheath tumor].
{Author}: Huang MX;Tang P;Cen TT;Jia XT;Sun C;Jin J;Lai NY;Chen ZB;Ding QL;Tao FY;Ma HY;
{Journal}: Zhonghua Jie He He Hu Xi Za Zhi
{Volume}: 47
{Issue}: 7
{Year}: 2024 Jul 12
暂无{DOI}: 10.3760/cma.j.cn112147-20240105-00011
{Abstract}: Malignant peripheral nerve sheath tumor (MPNST) frequently metastasizes to the lungs, although pleural metastasis is rare. This article reported a case of pleural metastasis of MPNST. The patient was a young man who presented with 1 week of shortness of breath with dry cough. He had a history of malignant peripheral nerve sheath tumor. The patient was diagnosed with MPNST pleural metastasis after a thoracoscopic pleural biopsy, which revealed short spindle cell hyperplasia, immunohistochemical staining for S-100(+), SOX-10(+), Ki-67(+) with a positive index of 20%, and H3K27Me3(-) in the pleural pathology.<BR>恶性周围神经鞘膜瘤（malignant peripheral nerve sheath tumor，MPNST）常转移至肺，胸膜转移罕见。本文报道1例MPNST胸膜转移患者。患者青年男性，因“气促伴干咳1周”就诊。既往恶性周围神经鞘膜瘤病史。内科胸腔镜胸膜活检病理提示短梭形细胞增生，胸膜病理切片免疫组织化学染色S-100（+）、SOX-10（+）、Ki-67（+）阳性指数20%、H3K27Me3（-），诊断为MPNST胸膜转移。.