{Reference Type}: Journal Article
{Title}: Analysis of optical properties and response mechanism of H2S fluorescent probe based on rhodamine derivatives.
{Author}: Sun G;Zhang RW;Chen XY;Chen YH;Zou LH;Zhang J;Li PG;Wang K;Hu ZG;
{Journal}: Spectrochim Acta A Mol Biomol Spectrosc
{Volume}: 321
{Issue}: 0
{Year}: 2024 Nov 15
{Factor}: 4.831
{DOI}: 10.1016/j.saa.2024.124745
{Abstract}: H2S plays a crucial role in numerous physiological and pathological processes. In this project, a new fluorescent probe, SG-H2S, for the detection of H2S, was developed by introducing the recognition group 2,4-dinitrophenyl ether. The combination of rhodamine derivatives can produce both colorimetric reactions and fluorescence reactions. Compared with the current H2S probes, the main advantages of SG-H2S are its wide pH range (5-9), fast response (30 min), and high selectivity in competitive species (including biological mercaptan). The probe SG-H2S has low cytotoxicity and has been successfully applied to imaging in MCF-7 cells, HeLa cells, and BALB/c nude mice. We hope that SG-H2S will provide a vital method for the field of biology.