{Reference Type}: Case Reports {Title}: Syphilis. {Author}: Nørfjand SB;Daugaard CA;Deleuran MS; {Journal}: Ugeskr Laeger {Volume}: 186 {Issue}: 27 {Year}: 2024 Jul 1 暂无{DOI}: 10.61409/V01240049 {Abstract}: This is a case report of 51-year-old male patient with various symptoms including skin rashes, sensory disturbances, and non-cicatricial hair loss. Despite previous tests, the cause remained elusive until a dermatological examination revealed signs of syphilis. The patient's history, including his sexual relationships, became key in confirming the diagnosis, leading to treatment for neurosyphilis. With a rising incidence of syphilis in Denmark, this case highlights the importance of considering syphilis as a potential diagnosis across medical specialities because of the diverse and challenging clinical manifestations.