{Reference Type}: Case Reports
{Title}: Epithelioid Hemangioendothelioma of Spleen and Bone: A Case Report.
{Author}: Denolf M;Rappaport A;Delvaux S;
{Journal}: J Belg Soc Radiol
{Volume}: 108
{Issue}: 1
{Year}: 2024
{Factor}: 1.912
{DOI}: 10.5334/jbsr.3600
{Abstract}: Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor that can originate in various parenchymatous organs, soft tissue, and bone. Extrahepatic involvement is exceedingly rare. In this case, multifocal disease in the spleen and bone was present. Bone lesions showed a target appearance. Splenic lesions showed delayed enhancement of solid components with persistent rim enhancement. A bone biopsy with CAMTA1 staining confirmed the diagnosis. Teaching point: The presence of multifocal bone and splenic lesions can raise suspicion of EHE when other multifocal diseases are excluded.