{Reference Type}: Journal Article
{Title}: Effect of Aging on Long-Term Functional Outcomes After Open Partial Laryngectomy.
{Author}: Cantaffa C;Donvito S;Manto AL;Serafini E;Caffagni R;Luppi MP;Tonelli R;Daniele M;Francesco M;
{Journal}: Otolaryngol Head Neck Surg
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 1
{Factor}: 5.591
{DOI}: 10.1002/ohn.863
{Abstract}: <B>OBJECTIVE: </B>Open partial horizontal laryngectomies (OPHLs) represent a comparable alternative to total laryngectomy and nonsurgical protocols in selected cases. While short-term functional outcomes of OPHLs have been widely investigated, few have focused on the effect of aging on residual laryngeal structures.<BR><B>METHODS: </B>Retrospective cohort study.<BR><B>METHODS: </B>Tertiary care academic center.<BR><B>METHODS: </B>Patients who underwent OPHLs after at least 1 year follow-up and optimal functional rehabilitation were included in the study. Swallowing function was assessed according to PAS (Penetration aspiration scale) and Pooling scores. Spectrogram analysis of voice was conducted according to Yanagihara classification and acoustic parameters were also recorded. Subjective questionnaire data about phonation and swallowing were also recorded. Data obtained were compared among patients according to age at time of surgery, evaluation and duration of follow-up.<BR><B>RESULTS: </B>Ninety-seven patients were enrolled with a mean age at surgery and evaluation of 63 and 70 years old, respectively. Median follow-up length was 5 years. OPHL type II was mostly performed. No significant correlation was observed between most of the analyzed variables and patient's age at the time of surgery and at the time of evaluation. Some acoustic parameters were negatively correlated with follow-up length, while Jitter, NHR (Noise-Harmonic Ratio), and Global grade and Roughness were significantly higher in patients >65 years old.<BR><B>CONCLUSIONS: </B>Patients who complete rehabilitation reach equally good results as their younger peers with stability over time. Finally, the effects of aging on residual larynx are of minor entity compared to the nonoperated patients.<BR><B>METHODS: </B>Level IV-retrospective cohort study.