{Reference Type}: Case Reports
{Title}: Case report: three ways to mitigate the risk of embolization during left atrial appendage closure in a patient with a massive and proximal left atrial appendage thrombus.
{Author}: Zendjebil S;Horvilleur J;Boilève V;Millien V;Garot P;
{Journal}: Eur Heart J Case Rep
{Volume}: 8
{Issue}: 6
{Year}: 2024 Jun
暂无{DOI}: 10.1093/ehjcr/ytae286
{Abstract}: <B>UNASSIGNED: </B>Left atrial appendage (LAA) thrombus is a contraindication for LAA closure (LAAC). However, in selected cases, oral anticoagulants are strictly contraindicated because of a history of life-threatening bleeding, and LAAC remains the only possible therapy to avoid systemic and especially cerebral embolization.<BR><B>UNASSIGNED: </B>We report a case of LAAC despite a massive proximal thrombus in a patient who had an absolute contraindication to anticoagulant therapy, with thorough pre-planning using CT scan, device modelling and thrombus trapping techniques to reduce the risk of systemic embolic events and perform LAAC safely.<BR><B>UNASSIGNED: </B>Although LAAC remains at high risk in this setting, the use of cautious techniques and tools, from pre-procedure planning to systemic embolization prevention systems associated to a precise transoesopheageal echocardiography guiding throughout the procedure, allows it to be performed as safely as possible when no other option is available.