{Reference Type}: Journal Article
{Title}: Impact of efavirenz on hormone-positive breast cancer survival in women living with HIV.
{Author}: Johnson AT;Ntloedibe T;Mendez Reyes JE;Matshaba MS;Dryden-Peterson SL;Chiao EY;
{Journal}: AIDS
{Volume}: 38
{Issue}: 9
{Year}: 2024 07 15
{Factor}: 4.632
{DOI}: 10.1097/QAD.0000000000003912
{Abstract}: Women living with HIV and breast cancer have poorer survival than HIV-negative women. Efavirenz-estrogen interactions are documented; however, the survival impact is unknown. Survival between women with estrogen-receptor positive breast cancer taking efavirenz (n = 38) and nonefavirenz regimens (n = 51) were compared. The 5-year overall-survival was 48.9% [95% confidence interval (CI) 33.0-72.2 and 51.1% (95% CI 34.0-76.8)] in the efavirenz and nonefavirenz groups, respectively suggesting efavirenz is unlikely driving poorer survival in women living with HIV and estrogen-receptor positive breast cancer.