{Reference Type}: Journal Article
{Title}: Hope on the Horizon? Aptamers in Diagnosis of Invasive Fungal Infections.
{Author}: Khodavaisy S;Xu J;
{Journal}: Genes (Basel)
{Volume}: 15
{Issue}: 6
{Year}: 2024 Jun 3
{Factor}: 4.141
{DOI}: 10.3390/genes15060733
{Abstract}: Despite remarkable advances in the diagnosis of invasive fungal infections (IFIs), rapid, specific, sensitive, and cost-effective detection methods remain elusive. Due to their stability, ease of production, and specificity to signature molecules of fungal pathogens, short single-stranded sequences of DNA, RNA, and XNA, collectively called aptamers, have emerged as promising diagnostic markers. In this perspective, we summarize recent progress in aptamer-based diagnostic tools for IFIs and discuss how these tools could potentially meet the needs and provide economical and simple solutions for point-of-care for better management of IFIs.