{Reference Type}: Journal Article
{Title}: Health professionals' perceptions of prehabilitation before haematopoietic cell transplantation to optimise candidacy in older adults.
{Author}: Guinan E;Heuston C;Sheill G;Chonghaile MN;Orfali N;
{Journal}: Support Care Cancer
{Volume}: 32
{Issue}: 7
{Year}: 2024 Jun 26
{Factor}: 3.359
{DOI}: 10.1007/s00520-024-08659-0
{Abstract}: <B>OBJECTIVE: </B>Haematologic malignancies for the most part are diseases of the elderly. Haematopoietic stem cell transplantation (HSCT) remains the only potentially curative strategy for many patients but carries substantial morbidity and mortality risks, particularly in frail or co-morbid patients. Pre-transplant optimisation of key targets through prehabilitation may have significant clinical impact.<BR><B>METHODS: </B>We utilised qualitative methodology (semi-structured interviews) to gain insights and understanding of the perceptions of medical, nursing and allied health professionals towards prehabilitation before haematopoietic cell transplantation to optimise candidacy in older adults. Thematic analysis was performed using a qualitative descriptive approach completed in duplicate by two researchers.<BR><B>RESULTS: </B>Between August and October 2023, eleven health professionals participated from four large cancer centres across the island of Ireland (n = 3 consultant haematologists, n = 7 specialist haematology nurses and n = 1 senior haematology physiotherapist). Four major themes were identified. The themes comprehensive biopsychosocial care and increasing demand for transplant in older patients highlight the unique challenges impacting older adults who receive HSCT. The multimodality pathways of care theme highlights the heterogeneity of treatment pathways across different clinical sites and disease types. This has implications for the prehabilitation: logistics and benefits theme, which indicated strong support for prehabilitation but emphasised that implementation must consider national reach and context.<BR><B>CONCLUSIONS: </B>There is broad national multidisciplinary interest in the development of prehabilitation programmes for patients being considered for transplant. Our results will inform the development of services in this area in consideration of national reach, malignancy-specific pathways and the unique factors associated with older age.