{Reference Type}: Case Reports
{Title}: Effective Endoscopic Submucosal Dissection of a Huge Esophageal Liposarcoma: A Case Report.
{Author}: Lee MJ;Lee MW;Joo DC;Hong SM;Baek DH;Lee BE;Kim GH;Song GA;
{Journal}: Korean J Gastroenterol
{Volume}: 83
{Issue}: 6
{Year}: 2024 Jun 25
暂无{DOI}: 10.4166/kjg.2024.047
{Abstract}: This case report presents the successful endoscopic submucosal dissection (ESD) of a well-differentiated esophageal liposarcoma in a 51-year-old male with persistent dysphagia. The cause was initially diagnosed as a 10 cm pedunculated lesion extending from the upper esophageal sphincter to the mid-esophagus. An ESD was chosen over traditional surgery because it is less invasive. The procedure involved a precise submucosal injection and excision with special techniques to manage bleeding from a central vessel. Despite the extraction challenges owing to the size of the lesion, it was successfully removed orally. A histopathological examination of the 8.3×4.2×2.3 cm specimen revealed the characteristic features of a well-differentiated liposarcoma, including MDM2 and CDK4 positivity. The follow-up revealed no recurrence, and active surveillance has been performed since. This report highlights the versatility of ESD in treating significant esophageal tumors and provides evidence for its efficacy as a minimally invasive alternative.