{Reference Type}: Journal Article
{Title}: REM and NREM Sleep Parasomnia in Anti-NMDA Receptor Encephalitis.
{Author}: Ribeiro L;Psimaras D;Vollhardt R;Honnorat J;Méneret A;Demeret S;Celier A;Valyraki NE;Cousyn L;Le Guennec L;Arnulf I;Gales AZ;
{Journal}: Neurol Neuroimmunol Neuroinflamm
{Volume}: 11
{Issue}: 5
{Year}: 2024 Sep
{Factor}: 11.36
{DOI}: 10.1212/NXI.0000000000200203
{Abstract}: <B>OBJECTIVE: </B>Encephalitis with anti-N-methyl-d-aspartate receptor antibodies (anti-NMDARe) is a rare disorder characterized by cognitive impairment, psychosis, seizures, and abnormal movements. Abnormal behaviors during REM sleep have not been described in anti-NMDARe.<BR><B>METHODS: </B>Patients were monitored by video-polysomnography on a first night followed by multiple sleep latency tests and 18 hours of bed rest.<BR><B>RESULTS: </B>Two patients with anti-NMDARe developed during the acute and postacute phase parasomnias including REM sleep behavior disorder and continuous finalistic quiet gesturing during a mixed N2/R sleep. The parasomnia disorder was improved by gabapentin and clonazepam.<BR><B>CONCLUSIONS: </B>Video-polysomnography avoids misdiagnosing these parasomnia behaviors for seizure or movement disorders and allows adequate treatment.