{Reference Type}: Case Reports {Title}: Acute Ischemic Stroke Superimposed on Acute Pulmonary Embolism in the Presence of Patent Foramen Ovale: A Case Report. {Author}: Alaboud Alkheder K;Al-Khafaji YB;Al-Nahhas OF; {Journal}: Cureus {Volume}: 16 {Issue}: 5 {Year}: 2024 May 暂无{DOI}: 10.7759/cureus.61036 {Abstract}: A patent foramen ovale (PFO) carries a high risk of paradoxical embolism. This risk is higher in certain conditions, including acute pulmonary embolism (APE). Although most patients with a PFO are asymptomatic, various clinical manifestations may be associated with PFO. Concomitant APE and acute ischemic stroke (AIS) due to paradoxical embolism from a PFO are rare. We report a case of a 61-year-old man who presented with simultaneous PE and AIS in the presence of PFO, was treated successfully with anticoagulation, and was discharged from the hospital neurologically intact.