{Reference Type}: Case Reports
{Title}: Primary achalasia diagnosed during pregnancy: rare cause of nausea and vomiting.
{Author}: Mei JY;Mendoza D;Gutierrez M;Rao R;
{Journal}: BMJ Case Rep
{Volume}: 17
{Issue}: 6
{Year}: 2024 Jun 24
暂无{DOI}: 10.1136/bcr-2023-258792
{Abstract}: Nausea and vomiting during pregnancy are very common; however, when persistent symptoms lead to severe malnutrition, other conditions should be considered. We present a patient with severe postprandial nausea and vomiting resulting in 120 lb weight loss. She was treated for presumed hyperemesis gravidarum but diagnosed with achalasia type 1 upon further work-up. The pregnancy was further complicated by fetal growth restriction, shortened cervix and preterm premature rupture of membranes, and resulted in delivery at 26 weeks of gestation. Postpartum, she underwent a peroral endoscopic myotomy procedure and has returned to normal body mass index.The differential for nausea/vomiting is broad, and major medical conditions can manifest for the first time during pregnancy. Severe malnutrition adversely affects maternal and fetal health. Further work-up should be pursued when symptoms cannot otherwise be explained.