{Reference Type}: Journal Article
{Title}: Profiling Numerical and Structural Chromosomal Instability in Different Cancer Types.
{Author}: Zhang X;Kschischo M;
{Journal}: Methods Mol Biol
{Volume}: 2825
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.1007/978-1-0716-3946-7_20
{Abstract}: Many cancers display whole chromosome instability (W-CIN) and structural chromosomal instability (S-CIN), referring to increased rates of acquiring numerically and structurally abnormal chromosome changes. This protocol provides detailed steps to analyze the W-CIN and S-CIN across cancer types, intending to leverage large-scale bulk sequencing and SNP array data complemented with the computational models to gain a better understanding of W-CIN and S-CIN.