{Reference Type}: Journal Article
{Title}: Effects of subclinical hypothyroidism in type II diabetes mellitus patients on biochemical, coagulation, and fibrinolysis status.
{Author}: Atia YA;Mohammed ST;Abdullah SS;Abbas AS;Fawzi HA;
{Journal}: J Adv Pharm Technol Res
{Volume}: 15
{Issue}: 2
{Year}: 2024 Apr-Jun
暂无{DOI}: 10.4103/JAPTR.JAPTR_89_24
{Abstract}: The aim of the currnet study to examine the effect of subclinical hypothyroidism (SCH) in diabetic patients on coagulation parameters. This retrospective case-control study involves 130 patients diagnosed with type 2 diabetes mellitus (T2DM), divided into 65 T2DM with newly diagnosed SCH and 65 euthyroid (EUT) T2DM patients without SCH. Fibrinogen (FIB) was significantly higher in SCH (508.2 ± 63.0 mg/dL) than EUT (428.1 ± 44.8 mg/dL). In the SCH patients, FIB correlated with several parameters, such as age (β = 0.396), body mass index (β = 0.578), glycated hemoglobin (β = 0.281), and activated partial thromboplastin time (β = 0.276). In conclusion SCH in DM patients appears to increase the magnitude of coagulopathy.