{Reference Type}: Journal Article
{Title}: FROM OUTER RETINAL NEOVACULARIZATION TO EXUDATIVE SUBRETINAL NEOVASCULARIZATION IN MACULAR TELANGIECTASIA TYPE 2.
{Author}: Krivosic V;Zureik A;Tadayoni R;Gaudric A;
{Journal}: Retina
{Volume}: 44
{Issue}: 7
{Year}: 2024 Jul 1
{Factor}: 3.975
{DOI}: 10.1097/IAE.0000000000004079
{Abstract}: <B>OBJECTIVE: </B>To describe the progression from outer retinal neovascularization (ORNV) to exudative subretinal new vessels (SRNVs) in idiopathic macular telangiectasia type 2.<BR><B>METHODS: </B>A total of 135 patients (270 eyes) imaged with optical coherence tomography angiography were included.<BR><B>METHODS: </B>Ellipsoid zone loss, outer retinal hyperreflectivity, ORNV, and SRNVs. Outer retinal neovascularization was defined as a flow signal passing through the outer plexiform layer, with or without vertical linear outer retinal hyperreflectivity on the optical coherence tomography B-scan. Subretinal new vessels were defined as an abnormal capillary network with a peripheral anastomotic arcade seen on en face optical coherence tomography angiography and a convex hyperreflectivity at the retinal pigment epithelium.<BR><B>RESULTS: </B>Subretinal new vessels were observed in 38/270 eyes (14%). Subretinal new vessels were at a fibrotic stage in 24/38 eyes and at an exudative stage in 6/38 eyes, and a progression from ORNV to SRNVs was documented in 8/38 eyes. All cases showed an ellipsoid zone loss. In seven eyes (2.5%), SRNVs were also associated with subepithelial neovascularization. No retinochoroidal anastomosis was detected. The visual acuity dropped when SRNVs were present.<BR><B>CONCLUSIONS: </B>In this case series, SRNVs were found in 14% of eyes. In all cases, they were associated with an ellipsoid zone loss and with outer retinal hyperreflectivity. A progression from ORNV to SRNVs was observed.