{Reference Type}: Journal Article
{Title}: SKELETAL HEALTH ASSESSMENT IN BRAZILIAN MEN WITH CELIAC DISEASE AT DIAGNOSIS: HOW IMPORTANT IS IT?
{Author}: Kotze LMDS;Skare TL;Kotze LR;Nisihara R;
{Journal}: Arq Gastroenterol
{Volume}: 61
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.1590/S0004-2803.24612024-005
{Abstract}: <B>BACKGROUND: </B>Low bone mass density (BMD) is an extraintestinal finding in celiac disease (CD). This may result in bone fractures leading to loss in quality of life.<BR><B>OBJECTIVE: </B>To assess BMD in male CD patients at diagnosis according to the patient's age.<BR><B>METHODS: </B>Descriptive retrospective carried out during the period between 2013 and 2023 in a single office that studied dual-energy X-ray absorptiometry (DXA) results in 28 male patients with a recent diagnosis of CD, divided into three groups: group 1 (age up to 18 years); group 2 (from 19 to 49 years of age) and group 3 (over 50 years of age). Were studied demographic and anthropometric parameters, time delay between symptoms onset and CD diagnosis and fracture occurrence.<BR><B>RESULTS: </B>Celiac patients studied had median age 36.0 years (IQR=16.5-50.7). Among them, 39.3% had osteopenia and 14.3% had osteoporosis. Only 36% of the sample had normal DXA values (group 1 with 37.5%; group 2 with 46% and group 3 with 14.2%). No pathological fracture was observed in this sample. CD diagnosis delay observed had median 1.0 year (IQR=1.0-4.7). When the number of individuals with normal and abnormal DXA results were compared, there was no difference in body mass index, time of diagnosis delay or Marsh classification (P=0.18).<BR><B>CONCLUSIONS: </B>Male patients at the time of CD diagnosis showed a high prevalence of low BMD, which was particularly evident in individuals over 50 years of age.