{Reference Type}: Journal Article {Title}: Investigation of Motor Learning Effects Using a Hybrid Rehabilitation System Based on Motion Estimation. {Author}: Takenaka K;Shima K;Shimatani K; {Journal}: Sensors (Basel) {Volume}: 24 {Issue}: 11 {Year}: 2024 May 29 {Factor}: 3.847 {DOI}: 10.3390/s24113496 {Abstract}: Upper-limb paralysis requires extensive rehabilitation to recover functionality for everyday living, and such assistance can be supported with robot technology. Against such a background, we have proposed an electromyography (EMG)-driven hybrid rehabilitation system based on motion estimation using a probabilistic neural network. The system controls a robot and functional electrical stimulation (FES) from movement estimation using EMG signals based on the user's intention, enabling intuitive learning of joint motion and muscle contraction capacity even for multiple motions. In this study, hybrid and visual-feedback training were conducted with pointing movements involving the non-dominant wrist, and the motor learning effect was examined via quantitative evaluation of accuracy, stability, and smoothness. The results show that hybrid instruction was as effective as visual feedback training in all aspects. Accordingly, passive hybrid instruction using the proposed system can be considered effective in promoting motor learning and rehabilitation for paralysis with inability to perform voluntary movements.