{Reference Type}: Journal Article
{Title}: Quality of Life for Adults with Prader-Willi Syndrome in Residential Group Homes.
{Author}: Mastey Ben-Yehuda H;Gross-Tsur V;Hirsch HJ;Genstil L;Derei D;Forer D;Benarroch F;
{Journal}: J Clin Med
{Volume}: 13
{Issue}: 11
{Year}: 2024 Jun 4
{Factor}: 4.964
{DOI}: 10.3390/jcm13113323
{Abstract}: Background: Strict regimens of restricted caloric intake and daily physical exercise are life-saving in Prader-Willi syndrome (PWS) but are extremely challenging in home environments. PWS-specialized hostels (SH) succeed in preventing morbid obesity and in coping with behavioral disorders; however, effects of restricted living environments on quality of life (QOL) have not been described. Evidence on QOL is critical for clinicians involved in placement decisions. Methods: We examined the impact of living in SH versus at home or in non-specialized hostels (H and NSH) on QOL, behavior, and health parameters. All 58 adults (26 males) followed-up in the National Multidisciplinary Clinic for PWS were included: 33 resided in SH, 18 lived at home, and 7 lived in NSH. Questionnaires were administered to primary caregivers to measure QOL, and data were obtained from the medical records. Results: The H and NSH group were compared with those for adults in SH. Despite strict diet and exercise regimens, QOL was similar for both groups. Eight-year follow-up showed that food-seeking behavior decreased in SH but increased in H and NSH. BMI, cholesterol, and triglyceride levels were lower in SH. Conclusion: Our results suggest that living in SH is associated with benefits for physical health and behavior without negatively affecting QOL.