{Reference Type}: Journal Article
{Title}: 'Old is gold' does conventional test tube method still reign supreme? An immuno-haematological survey of anti-D detection and titration in ante-natal cases among major hospitals across India.
{Author}: Pandey P;Marik A;Tiwari A;Das SS;Shastry S;Chowdhry M;Kumari S;
{Journal}: Transfus Med
{Volume}: 34
{Issue}: 4
{Year}: 2024 Aug 18
{Factor}: 2.057
{DOI}: 10.1111/tme.13057
{Abstract}: <B>BACKGROUND: </B>Anti-D detection and titration plays a major role in RhD negative antenatal cases both, for monitoring maternal as well as fetal status as well as initiation of early therapeutic interventions, such as intra-uterine transfusions (IUT) to improve maternal as well as fetal morbidity and mortality and reduce the adverse effects of haemolytic disease of fetus and newborn (HDFN). We conducted a survey focusing on the policies and procedures of anti-D detection and titration among major tertiary care centres across India.<BR><B>METHODS: </B>The survey was drafted by a working group of transfusion medicine and immunohematology specialists from six different centres in India. Data were obtained via the use of an online questionnaire.<BR><B>RESULTS: </B>Results were categorised into four categories, Hospital information, immuno-haematological testing methodology, clinical significance of anti-D testing and the role of transfusion medicine specialists. The survey highlighted the modalities as well as the methodologies of anti-D detection and titration in antenatal women across different major tertiary care centres in India.<BR><B>CONCLUSIONS: </B>This survey provided a unique snapshot of the prevalent methodologies being employed by major tertiary care centres across the country for detection and titration of anti-D levels as well as the important role it plays in the therapy of affected antenatal women to minimise adverse effects on the fetus.