{Reference Type}: Journal Article {Title}: The Use of Dermal Substitute in the Treatment of Burns as a Complication of Type 2 Diabetes Mellitus and Diabetic Foot Syndrome. {Author}: Tedeschi A;Salutini E;Cosentino C;Poggi CD;Becherini R;Fusilli D;Anichini R; {Journal}: Int J Low Extrem Wounds {Volume}: 0 {Issue}: 0 {Year}: 2024 Jun 18 {Factor}: 1.922 {DOI}: 10.1177/15347346241262061 {Abstract}: Diabetic Foot Syndrome is a complex and challenging clinical condition associated with high risk of mortality and lower limb amputation. The distal lesions represent the epiphenomenon of this syndrome and request a multidisciplinary care and an appropriate therapeutic path to ensure their healing. This case report describes the management of burns in a patient with type 2 diabetes mellitus, end stage renal disease and Diabetic Foot Syndrome. The lesions were treated with autologous epidermal skin graft until healing. Products that stimulate or replace extracellular matrix, which has a central role in wound healing, can be consider in the treatment of burns and offer a simpler and less disabling reconstructive possibility for the patient.