{Reference Type}: Journal Article
{Title}: Global burden, trends, and cross-country inequalities of urinary tract infections in adolescents and young adults, 1990-2019.
{Author}: Deng H;Zhao Y;Zou Q;Chen Z;Liao X;
{Journal}: Am J Infect Control
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jun 15
{Factor}: 4.303
{DOI}: 10.1016/j.ajic.2024.06.007
{Abstract}: <B>BACKGROUND: </B>Limited studies have evaluated the global burden, trends, and cross-country inequalities for urinary tract infections (UTIs) in adolescents and young adults (AYAs).<BR><B>METHODS: </B>Age-standardized rates (ASRs) of incidence (ASIR), mortality (ASMR) and Disability-Adjusted Life Years (DALYs) (ASDR) were used to describe the UTI burden. The estimated annual percentage changes (EAPCs) were calculated to evaluate the temporal trends from 1990 to 2019. The slope index of inequality and concentration index were utilized to quantify the distributive inequalities in the burden of UTIs.<BR><B>RESULTS: </B>From 1990 to 2019, a significant increase in ASIR (EAPC=0.22%, 95% CI 0.19% to 0.26%) was found for UTIs in AYAs, and the increasing trend was more pronounced in males than females. Significant decreases in ASMR and ASDR were found for UTIs in females but not in males. The slope index of inequality changed from 21.80 DALYs per 100,000 in 1990 to 20.91 DALYs per 100,000 in 2019 for UTIs in AYAs. Moreover, the concentration index showed -0.23 in 1990 and -0.14 in 2019 for UTIs in AYAs.<BR><B>CONCLUSIONS: </B>Countries with lower sociodemographic development levels shouldered a disproportionately higher burden of UTIs and should be targeted for strengthening their national programmes.<BR><B>CONCLUSIONS: </B>UTIs remain an ongoing health burden for AYAs globally, with a substantial heterogeneity found across countries, sex, and age groups.