{Reference Type}: Case Reports {Title}: Herpes Zoster Ophthalmicus Secondary to Periorbital Cellulitis. {Author}: Sheth K;Lee C;Jangda M;Baah Y; {Journal}: Cureus {Volume}: 16 {Issue}: 5 {Year}: 2024 May 暂无{DOI}: 10.7759/cureus.60453 {Abstract}: Varicella zoster virus (VZV) infection, also commonly known as chickenpox, is a communicable disease most often contracted in childhood via contact, airborne, or droplet transmission. After about a two-week incubation period, patients can experience a prodromal phase, which includes a pruritic vesicular blistering rash with associated constitutional symptoms such as fever, headache, malaise, muscle aches, fatigue, and sore throat. Symptoms are often self-limiting and only require supportive care and observation. We report a case of a 54-year-old female who presented with an unusual background history and was found to have a rare manifestation of herpes zoster virus, presenting as herpes zoster ophthalmicus (HZO).