{Reference Type}: Letter {Title}: Aspects related to the inference of causality in cross-sectional studies. Comments on: "8-Hydroxy-2'-deoxyguanosine protein immunoexpression is associated with the pathogenesis of actinic cheilitis". {Author}: Martins IMC;Miola AC;Garbers LEFM;Miot HA; {Journal}: An Bras Dermatol {Volume}: 99 {Issue}: 5 {Year}: 2024 Sep-Oct 13 {Factor}: 2.113 {DOI}: 10.1016/j.abd.2024.03.002