{Reference Type}: Journal Article
{Title}: Timed barium esophagography to predict recurrent achalasia after peroral endoscopic myotomy: a retrospective study in Thailand.
{Author}: Suwatthanarak T;Phalanusitthepa C;Thongchuam C;Akaraviputh T;Chinswangwatanakul V;Tawantanakorn T;Leelakusolvong S;Maneerattanaporn M;Apisarnthanarak P;Wasinrat J;
{Journal}: Clin Endosc
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jun 14
暂无{DOI}: 10.5946/ce.2023.236
{Abstract}: <B>UNASSIGNED: </B>Achalasia is a rare esophageal motility disease, for which peroral endoscopic myotomy (POEM) has emerged as a promising treatment option; however, recurrence remains a challenge. Timed barium esophagography (TBE) is a useful diagnostic tool and potential outcome predictor of achalasia. This study aimed to determine predictive tools for recurrence after POEM.<BR><B>UNASSIGNED: </B>This retrospective study enrolled achalasia patients who underwent POEM between January 2015 and December 2021. Patients were categorized into two groups using the 1-month post-POEM Eckardt scores and TBE: the discordant group (Eckardt score improved >50%, TBE decreased <50%) and the concordant group (both Eckardt score and TBE improved >50%). Recurrence was defined as a reincrease in the Eckardt score to more than three during follow-up.<BR><B>UNASSIGNED: </B>Complete medical records were available in 30 patients who underwent POEM. Seventeen patients (56.7%) were classified into the discordant group, while 13 patients (43.3%) were in the concordant group. The overall recurrence rate was 11.9% at 1-year, increasing to 23.8% during the extended follow-up. The discordant group had a 6.87 fold higher recurrence rate than the concordant group (52.9% vs. 7.7%, p=0.017).<BR><B>UNASSIGNED: </B>These results strongly suggest that combining the Eckardt score with TBE can effectively predict recurrent achalasia after POEM. Patients in the discordant group had an elevated risk.