{Reference Type}: Journal Article {Title}: shinyCircos-V2.0: Leveraging the creation of Circos plot with enhanced usability and advanced features. {Author}: Wang Y;Jia L;Tian G;Dong Y;Zhang X;Zhou Z;Luo X;Li Y;Yao W; {Journal}: Imeta {Volume}: 2 {Issue}: 2 {Year}: 2023 May 暂无{DOI}: 10.1002/imt2.109 {Abstract}: We previously developed shinyCircos, an interactive web application for creating Circos diagrams, which has been widely recognized for its graphical user interface and ease of use. Here, we introduce shinyCircos-V2.0, an upgraded version of shinyCircos that includes a new user interface with enhanced usability and many new features for creating advanced Circos plots. To help users get started with shinyCircos-V2.0, we provide detailed tutorials and example input data sets. The application is available online at https://venyao.xyz/shinyCircos/ and https://asiawang.shinyapps.io/shinyCircos/, or can be installed locally using the source code deposited in GitHub (https://github.com/YaoLab-Bioinfo/shinyCircos-V2.0).