{Reference Type}: Journal Article
{Title}: Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution.
{Author}: Zhang X;Blaxter M;Wood JMD;Tracey A;McCarthy S;Thorpe P;Rayner JG;Zhang S;Sikkink KL;Balenger SL;Bailey NW;
{Journal}: Nat Commun
{Volume}: 15
{Issue}: 1
{Year}: 2024 Jun 12
{Factor}: 17.694
{DOI}: 10.1038/s41467-024-49344-4
{Abstract}: Theory predicts that compensatory genetic changes reduce negative indirect effects of selected variants during adaptive evolution, but evidence is scarce. Here, we test this in a wild population of Hawaiian crickets using temporal genomics and a high-quality chromosome-level cricket genome. In this population, a mutation, flatwing, silences males and rapidly spread due to an acoustically-orienting parasitoid. Our sampling spanned a social transition during which flatwing fixed and the population went silent. We find long-range linkage disequilibrium around the putative flatwing locus was maintained over time, and hitchhiking genes had functions related to negative flatwing-associated effects. We develop a combinatorial enrichment approach using transcriptome data to test for compensatory, intragenomic coevolution. Temporal changes in genomic selection were distributed genome-wide and functionally associated with the population's transition to silence, particularly behavioural responses to silent environments. Our results demonstrate how 'adaptation begets adaptation'; changes to the sociogenetic environment accompanying rapid trait evolution can generate selection provoking further, compensatory adaptation.