{Reference Type}: Journal Article
{Title}: Do oligodendrocytes regulate axonal glucose uptake and consumption?
{Author}: Fletcher JL;Young KM;
{Journal}: Trends Neurosci
{Volume}: 47
{Issue}: 8
{Year}: 2024 Aug 11
{Factor}: 16.978
{DOI}: 10.1016/j.tins.2024.06.001
{Abstract}: Neurons have high energy demands. In a recent study, Looser et al. identified oligodendrocyte Kir4.1 as the activity-dependent driver of oligodendrocyte glycolysis that ensures that lactate is supplied to active neurons. Given that oligodendrocyte Kir4.1 also influenced axonal glucose consumption and uptake, oligodendrocytes may play a broader role in neuronal metabolic regulation.