{Reference Type}: Journal Article
{Title}: Amylin-like immunoreactivity in the extra-islet peptide YY-producing and glucagon-immunoreactive cells in Japanese quail pancreas.
{Author}: Yanagida B;Yamamoto T;Suzuki H;
{Journal}: Anat Histol Embryol
{Volume}: 53
{Issue}: 4
{Year}: 2024 Jul
{Factor}: 1.13
{DOI}: 10.1111/ahe.13074
{Abstract}: In this study, we investigated amylin-like substance distribution in the pancreas of Japanese quail (Coturnix japonica) using a specific anti-rat amylin serum. We detected amylin-immunoreactive cells dispersed in the pancreatic extra-islet region but not in the islet region. The synthetic rat amylin-containing serum pre-absorption abolished the staining profile. Almost all amylin-immunoreactive cells were immuno-positive for peptide YY (PYY). In addition, certain amylin-immunoreactive cells stained immuno-positive for glucagon. Amylin and PYY co-secreted from the extra-islet cells might participate in the insulin and glucagon release regulation in the pancreas and food intake modulation through the central nervous system.