{Reference Type}: Journal Article {Title}: The Hippocratic principle "to help or at least to do no harm". {Author}: Askitopoulou H; {Journal}: Transfus Clin Biol {Volume}: 31 {Issue}: 3 {Year}: 2024 Aug 6 {Factor}: 2.126 {DOI}: 10.1016/j.tracli.2024.06.002 {Abstract}: Hippocrates' teaching on the ethical and moral values of medicine have captivated physicians, scholars, and historians for over twenty-five centuries, enduring despite the challenges of applying moral guidance across diverse cultures. At the core of Hippocratic ethics is the human relationship between the physician and the patient, with an emphasis on the physician's responsibility to assess potential harm involved in any attempt to heal. The Hippocratic principle "to help, or at least to do no harm" remains as relevant today as it was 2,500 years ago. In the modern context, it serves as a deontological imperative, reminding physicians to evaluate the risks of harm associated with any healing attempt. This concept aligns with the ethical principles of beneficence and non-maleficence, which are at the heart of Hippocratic medical ethics with timeless significance.