{Reference Type}: Journal Article {Title}: Potentials of Ulva spp.-derived sulfated polysaccharides as gelling agents with promising therapeutic effects. {Author}: Kraithong S;Bunyameen N;Theppawong A;Ke X;Lee S;Zhang X;Huang R; {Journal}: Int J Biol Macromol {Volume}: 273 {Issue}: 0 {Year}: 2024 Jul 5 {Factor}: 8.025 {DOI}: 10.1016/j.ijbiomac.2024.132882 {Abstract}: Ulvan, a sulfated polysaccharide extracted from Ulva spp., has garnered significant attention in the food and pharmaceutical industries due to its potential health benefits. These include immunomodulation, antiviral, anti-inflammatory, anti-hyperlipidemic, and anti-cancer effects. Nonetheless, practical applications in these fields remain limited due to an incomplete understanding of its gelation mechanisms. Additionally, the underlying mechanisms of its gelation have not been completely understood and thoroughly reviewed. The primary objective is to provide current insights into ulvan's gelling mechanisms and potential health impacts. This review also delves into the existing applications of ulvan polysaccharides. By unraveling these aspects, the information provided in this work is expected to deepen our understanding of ulvan's gelation mechanisms and its prospective role in enhancing health, holding promise for advancements in the fields of food science and disease prevention. This work's theoretical insights contribute significantly to a deeper understanding of these aspects, which holds paramount importance in unleashing the full potential of ulvan and elevating its scientific significance.