{Reference Type}: Journal Article
{Title}: HOW I DO IT: Cushing's disease-selective adenomectomy via an endoscopic transsphenoidal approach.
{Author}: Phillips N;Nix P;De Santos M;
{Journal}: Acta Neurochir (Wien)
{Volume}: 166
{Issue}: 1
{Year}: 2024 Jun 6
{Factor}: 2.816
{DOI}: 10.1007/s00701-024-06078-y
{Abstract}: <B>BACKGROUND: </B>An ACTH-secreting pituitary adenoma is the most common cause of excessive endogenous glucocorticoid production resulting in Cushing's Syndrome. A multidisciplinary approach is paramount. Selective adenomectomy is the treatment of choice.<BR><B>METHODS: </B>Endoscopic transnasal transsphenoidal approach to the tumour, along with techniques for resection, are demonstrated.<BR><B>CONCLUSIONS: </B>Endoscopic transsphenoidal approaches with its magnified view of the pituitary gland allows precise microsurgical dissection during selective adenomectomy. This technique increases the possibility of proving a gross total resection, leading to clinical and biochemical cure in these patients.